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Turning Flatiron into Gold

Medical Aesthetics + Wellness in Flatiron, NY

40 E. 21st Street, New York, NY

Your confidence deserves expert care. Discover refined, natural results with our specialized aesthetics and wellness providers in the heart of Flatiron.

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Mon: 10 :00am – 7:00pm Today's Hours
Tue: 10 :00am – 7:00pm Today's Hours
Wed: 10 :00am – 7:00pm Today's Hours
Thur: 10 :00am – 7:00pm Today's Hours
Fri: 10 :00am – 7:00pm Today's Hours
Sat: 10 :00am – 6:00pm Today's Hours
Sun: Closed Today's Hours
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Expert-Led Aesthetic Care in Flatiron, NY

Personalized Treatment Plans Tailored for You

Wellness Backed by Science

Led by Women, Founded for Excellence

Enhancements That Look Natural

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alchemy

noun: a magical process involving creation, transformation, and combination

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43

the number of facial muscles

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New Client Offers

New to Alchemy 43? Save up to 50% on your initial service.

50% Off

First Syringe of Filler

20 Free Units of Botox

With Purchase of 20 Units

50% Off

First Microneedling with PRP

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Our clients say it best

“I still look like myself, but better.”

“This was my first time at Alchemy 43, and it was such a great experience! The customer service was phenomenal, and I was in and out very quickly. The clinic is so beautiful and clean, and the girls are very friendly and knowledgeable! Kelsey did my Botox, and everything was great!! I will most definitely be returning! 10 out of 10!”

— TY | Dallas, TX

“I don’t have enough words to explain my overall visit and results. Nurse Heather has an eye for balancing the face and has wonderful techniques. My results look natural and I look so refreshed. Manager Heather went above and beyond to answer all my questions and concerns. She literally picked up the phone every time I called. …Thank you both for your time and your exceptional service. Xoxo.”

— JS | Newport Beach, CA

“I feel so heard and am treated with such kindness and respect here! I look back at old pictures of myself and I wish I didn’t wait so long to get Botox and lip filler! I feel so much more confident. Pegah and Haley (and Heather too!) are always so sweet and assure me I am beautiful. They are not pushy with procedures like I’ve experienced at other places. They walk me through everything and give honest and sincere advice. I trust them because they have me looking amazing!!! I can’t recommend this place enough!”

— HG | Newport Beach, CA

“Alchemy is the best place in Newport for Botox and all your peptide and injectable needs! Heather, Heather RN, and Haley RN always brighten my day with their smiles, and the store is designed so cute. I highly recommend everyone check out this place. As a member you save so much money!”

— HS | Newport Beach, CA

“The staff was great. I felt heard and my desires were met! I also liked that my injector was really knowledgeable and conservative where needed! I will be coming back!”

— SW | Flatiron, NY

“Walking through the door into a beautiful serene space, I was greeted by friendly and welcoming personnel. The treatments I had have all been amazing—I love the results. The aestheticians are extremely knowledgeable and professional. They patiently listened to my concerns and gave me their expert advice on what would give me the best results. I'm so happy I did. The results are above and beyond my expectations. I would never go anywhere else.”

— MF | West Hollywood, CA

“It's only been 24 hours since Tiffany did my Botox and the results are already the best I've ever had. Witchcraft. Sorcery. I will never see anyone else.”

SY | West Hollywood, CA

“Kelsey is the only person I’ll ever trust with my injections! She’s incredibly knowledgeable, truly listens to your needs, and always offers expert advice. On top of that, she makes you feel completely at ease. I can’t recommend her and Alchemy 43 enough!”

— MT | Dallas, TX

“Alchemy 43 is my go-to and holy grail when it comes to injections & esthetics!! They make you feel so comfortable and there’s not a single injector I wouldn’t trust. I also love how comfortable my boyfriend feels when he gets his Botox done! Will definitely be returning.”

— HF | Dallas, TX

“Absolutely love Alchemy 43 Uptown in Houston! Dejae and Marquita are hands down the best I’ve had. They go above and beyond to calm my nerves (I’m a wuss about pain!) and my results are amazing too! Don’t hesitate to visit for any of your Botox or filler needs!”

— JT | Houston, TX

“Dejay gives a phenomenal experience right when you walk through the door! Caroline did my lips, and I am so pleased with the results. Both of them speak with intelligence and give me all the knowledge I need, including after-care/etc! Not only are both of them great at what they do, they are kind and have warming smiles!”

— JH | Houston, TX

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Your Formula for Confidence

Signature Aesthetic + Wellness Services in Flatiron, NY

From the instant you step into our Flatiron clinic, your individual experience becomes our focus. Discover a welcoming space designed with a touch of elevated comfort and effortless style. Our expert aesthetic providers prioritize listening to your unique desires, guiding you through tailored treatments to enhance your specific features. Our goal is to leave you feeling refreshed, self-assured, and completely at ease in your own skin.

Wrinkle Reducers Filler Medical Weight Loss Hair Rejuvenation Microneedling Platelet-Rich Plasma (PRP)
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Tailored Precision

Botox® in Flatiron, NY

Our skilled injectors approach neuromodulator treatments, including Botox, Dysport, and Letybo, with precision and artistry, softening lines, enhancing facial harmony, and elevating your natural expressions for a refreshed, authentic appearance.

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Subtle & Impeccable

Dermal Fillers in Flatiron, NY

We blend expertise with a balanced approach to enhance your natural beauty. Using dermal fillers, our skilled injectors subtly accentuate your facial features with precision and care, ensuring a natural look that truly reflects who you are.

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Your Goals, On Your Terms

Medical Weight Loss in Flatiron, NY

Weight management is a personal journey. At our Flatiron clinic, we offer a medically guided and holistic approach tailored to your unique body, goals, and lifestyle to nurture every aspect of your well-being.

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Natural Renewal Through Science

PRP Hair Rejuvenation in Flatiron, NY

Enhance healthy hair growth with our PRP treatments, collaborating with your body to restore balance and vitality.

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Kickstart Natural Collagen

Advanced Microneedling in Flatiron, NY

Boost your skin's collagen production with advanced microneedling, refining texture for a youthful radiance from within.

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Harness Your Inner Glow

Platelet-Rich Plasma (PRP) Treatments in Flatiron, NY

Unleash your skin and hair's natural glow with PRP treatments. By harnessing the power of your body's own growth factors, PRP encourages rejuvenation from within.

A Vision for Modern Aesthetics

Meet Our Founder, Nicci Levy

Nicci Levy founded Alchemy 43 after years working inside the cosmetics industry, recognizing a need for a new kind of experience—one that felt elevated yet approachable. For Nicci, aesthetic care should never feel like “fixing” but rather enhancing what already makes you unique.

At our Flatiron studio, Nicci's vision comes to life through subtle, natural treatments delivered by expert injectors. It’s a space where confidence grows without overcorrection, and where results are designed to integrate seamlessly into your lifestyle.

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Expertise That Inspires Trust

Meet the Flatiron Team

In the heart of Flatiron, the Alchemy 43 team blends artistry with medical precision. Each provider is carefully selected for their advanced training and specialized skill in injectables.

Our philosophy is simple: empower clients by delivering subtle enhancements that elevate, never overwhelm. With a commitment to refined results and a seamless client experience, our team ensures that every visit leaves you feeling confident, cared for, and authentically yourself.

A New Era of Wellness

Wellness Services in Flatiron, NY

Our science-driven wellness treatments are designed to work with your body, seamlessly blending holistic balance with innovation. From physician-guided weight management programs to regenerative therapies that renew from within, our Flatiron providers deliver care that refines both appearance and overall vitality. Here, wellness isn’t a trend; it’s an intentional, elevated approach to feeling and looking your best.

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Your Aesthetic Advantage

Join Now in Flatiron

Enjoy monthly savings on your favorite services and products, receive special discounts that aren't available to non-members, and enjoy additional perks designed just for you.

Shop Now

Skincare & Supplements

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Radiance for Every Occasion

Special Event Prep in Flatiron

We know your calendar is full of moments worth celebrating. Our special event prep treatments are designed to highlight your best features and help you feel your most confident. Whether you’re preparing for a wedding, an important presentation, or a night out in the city, our expert providers tailor your plan so you arrive polished, radiant, and completely camera-ready.

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Share the Glow 

Refer a Friend & Earn!

We know that confidence is even better when it’s shared. Invite your friends to experience Alchemy 43 and enjoy rewards together. For every friend who books using your referral link, you’ll receive $100 toward your next treatment—and they’ll enjoy savings on their first visit. Because glowing skin looks even better when it’s part of your circle.

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Find Your Nearest Clinic

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